Specific experimental design combinations used to develop mathematical models with linear, quadratic, and interaction terms to seek optimum performance from a given set of factors and response variables.
Response surface method (RSM) explores the relationships between several explanatory variables and one or more response variables. The method was introduced by G. E. P. Box and K. B. Wilson in 1951. The main idea of RSM is to use a sequence of designed experiments to obtain an optimal response. Box and Wilson suggest using a second-degree polynomial model to do this. They acknowledge that this model is only an approximation, but use it because such a model is easy to estimate and apply, even when little is known about the process.